HTB-176 H9 人急性淋巴母細(xì)胞白血病細(xì)胞

ATCC® Number: HTB-176™ Price: $268.00

Designations:

H9 [derivative of HuT 78]

Depositors: RC Gallo, M Popovic

Biosafety Level: 1

Shipped: frozen

Medium & Serum: See Propagation

Growth Properties: suspension

Organism: Homo sapiens （human）

Morphology: lymphoblast

HTB-176 H9 人急性淋巴母細(xì)胞白血病細(xì)胞

Source: Disease: lymphoma

Cell Type: cutaneous T lymphocyte;

Cellular Products: interleukin-2 （interleukin 2, IL-2）

Permits/Forms: In addition to the MTA mentioned above, other ATCC and/or regulatory permits may be required for the transfer of this ATCC material. Anyone purchasing ATCC material is ultimay responsible for obtaining the permits. Please click here for information regarding the specific requirements for shipment to your location.

Applications: transfection host （Roche FuGENE® Transfection Reagents）

Receptors: interleukin 2 （IL-2）

Virus Susceptibility: human immunodeficiency virus 1 （HIV-1, also known as HTLV-III or LAV）

Tumorigenic: Yes

Antigen Expression: CD4;

HLA A1, B62, C3, DR4, DQ3

DNA Profile （STR）: Amelogenin: X,Y

CSF1PO: 11

D13S317: 8,12

D16S539: 11,12

D5S818: 11

D7S820: 8,11

THO1: 8,

9

TPOX: 8,9

vWA: 14,15

Cytogenetic Analysis: This is a near triploid cell line （modal number = 69; range = 58 to 74）. The frequency of higher ploidies is 2.5%. The line has an extremely complex karyotype with nearly 60% of the chromosomes in each cell being structurally altered marker chromosomes., Among the markers are t（3p4q）, t（5q6q）, t（5p6p）, i（18q）, i（18p）; t（4q7p）, and del（7）（q32）. The first four of these are usually paired. Normal N4, N5, N6, N7, N10, N13, N18, N19, N20 an X are absent.

Isoenzymes: AK-1, 0

HTB-176 H9